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This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
14-3-3; 14-3-3 protein tau; 14-3-3 protein T-cell; 14-3-3 protein theta; 14-3-3 tau; 14-3-3 theta; 14-3-3t; 1C5; 2700028P07Rik; AA409740; AU021156; HS1; OTTHUMP00000165887; Protein HS1; protein tau; protein, theta; R74690; tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Unknown (protein for MGC:127486); YWHAQ
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